Performance & GH axis
Ipamorelin
Growth Hormone Secretagogue
One of the mildest and most selective growth hormone releasing peptides. Stimulates growth hormone without significantly affecting cortisol or prolactin levels.
Also known as: Ipam
- Status
- Ipamorelin is a research compound and not approved by the FDA for human use.
- Evidence
- Early human data. Only small or early-phase studies in people so far.
- Half-life
- ~2 hours
- How it's taken
- Subcutaneous injection, typically 2-3x daily
- Mechanism
- Growth-hormone secretagogue
- Pathways
- GH-releasing peptide, GH axis
How Ipamorelin works
Acts on the ghrelin receptor in the pituitary gland to stimulate growth hormone release in a pulsatile (natural wave-like) pattern, mimicking your body's own rhythm of GH production.
What research has looked at
- Clean growth hormone release
- Anti-aging effects on skin and joints
- Improved sleep and recovery
- Better body composition
- Minimal side effect profile
Evidence level: Early human data. Only small or early-phase studies in people so far. These are areas studied or reported, not promised effects.
Reported side effects and risks
- Mild headache
- Temporary water retention
- Slight increase in hunger
- Injection site redness
- Rare: dizziness
Sources
- PubMed research on ipamorelin growth hormone secretagogue · NIH · National Library of Medicine
- DrugBank record for ipamorelin · DrugBank
- Active clinical trials for ipamorelin · U.S. National Library of Medicine
Track Ipamorelin in Peptide Vault
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Ipamorelin FAQ
What is Ipamorelin?
One of the mildest and most selective growth hormone releasing peptides. Stimulates growth hormone without significantly affecting cortisol or prolactin levels.
How does Ipamorelin work?
Acts on the ghrelin receptor in the pituitary gland to stimulate growth hormone release in a pulsatile (natural wave-like) pattern, mimicking your body's own rhythm of GH production.
Is Ipamorelin FDA approved?
No. Ipamorelin is a research compound and not approved by the FDA for human use. Evidence level: early human data. Only small or early-phase studies in people so far.
What is the half-life of Ipamorelin?
Reported half-life: ~2 hours.
How is Ipamorelin taken?
Subcutaneous injection, typically 2-3x daily.
What side effects have been reported with Ipamorelin?
Reported in the sources: Mild headache; Temporary water retention; Slight increase in hunger; Injection site redness; Rare: dizziness.
Educational summary compiled from the sources listed above. Not medical advice. Peptide Vault does not sell, source or recommend any compound. Talk to a qualified clinician before starting or changing anything.