Research compounds
Vesugen
Lys-Glu-Asp, KED peptide
Vesugen is a synthetic tripeptide (lysyl-glutamyl-aspartyl) from the same Khavinson bioregulator family as Pinealon, marketed for vascular health. It is not approved by the FDA or EMA and has no substantive Western clinical evidence.
Also known as: Lys-Glu-Asp, KED peptide
- Status
- Vesugen is a research compound and not approved by the FDA for human use.
- Evidence
- Anecdotal. Mostly community reports; there is no controlled human data.
- Half-life
- Not established.
- How it's taken
- Oral capsule in non-clinical use
- Mechanism
- Mitochondrial / longevity
How Vesugen works
As with the other Khavinson bioregulators, the proposed mechanism is tissue-specific regulation of gene expression through direct peptide-DNA interaction — here targeting vascular endothelium. This mechanism has not been independently validated outside the originating research group and is not accepted as established pharmacology.
What research has looked at
- Russian-language sources report effects on endothelial function in laboratory models.
- The tripeptide is small enough that oral absorption is plausible in principle.
- As with the rest of the bioregulator family, it has a long history of use in Russia and a correspondingly long, if uncontrolled, record of tolerability.
Evidence level: Anecdotal. Mostly community reports; there is no controlled human data. These are areas studied or reported, not promised effects.
Reported side effects and risks
- The proposed mechanism has not been independently replicated, and the bioregulator literature sits outside mainstream peer-reviewed pharmacology.
- No controlled Western clinical trials exist and no regulator has approved it.
- Cardiovascular claims are unsupported by controlled human outcome data, and cardiovascular disease is precisely the setting where surrogate markers have repeatedly failed to predict outcomes.
- Material sold as Vesugen is supplement or research chemical supply with unverified identity, purity and dose accuracy.
- Long-term safety in humans is unstudied.
Sources
- PubMed research on Vesugen KED peptide bioregulator · NIH · National Library of Medicine
- DrugBank record for Vesugen · DrugBank
- Active clinical trials for Vesugen · U.S. National Library of Medicine
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Related compounds
Vesugen FAQ
What is Vesugen?
Vesugen is a synthetic tripeptide (lysyl-glutamyl-aspartyl) from the same Khavinson bioregulator family as Pinealon, marketed for vascular health. It is not approved by the FDA or EMA and has no substantive Western clinical evidence.
How does Vesugen work?
As with the other Khavinson bioregulators, the proposed mechanism is tissue-specific regulation of gene expression through direct peptide-DNA interaction — here targeting vascular endothelium. This mechanism has not been independently validated outside the originating research group and is not accepted as established pharmacology.
Is Vesugen FDA approved?
No. Vesugen is a research compound and not approved by the FDA for human use. Evidence level: anecdotal. Mostly community reports; there is no controlled human data.
How is Vesugen taken?
Oral capsule in non-clinical use.
What side effects have been reported with Vesugen?
Reported in the sources: The proposed mechanism has not been independently replicated, and the bioregulator literature sits outside mainstream peer-reviewed pharmacology; No controlled Western clinical trials exist and no regulator has approved it; Cardiovascular claims are unsupported by controlled human outcome data, and cardiovascular disease is precisely the setting where surrogate markers have repeatedly failed to predict outcomes; Material sold as Vesugen is supplement or research chemical supply with unverified identity, purity and dose accuracy; Long-term safety in humans is unstudied.
Educational summary compiled from the sources listed above. Not medical advice. Peptide Vault does not sell, source or recommend any compound. Talk to a qualified clinician before starting or changing anything.