Skin & cosmetic
GHK-Cu
Copper Peptide
A naturally occurring peptide in human blood that decreases with age. When bound to copper, it becomes a powerful signal for tissue remodeling and skin repair.
Also known as: GHK Copper
- Status
- GHK-Cu is used as a cosmetic or over-the-counter ingredient, not as an approved drug.
- Evidence
- Early human data. Only small or early-phase studies in people so far.
- Half-life
- ~12 hours (topical effects persist longer)
- How it's taken
- Topical cream/serum or subcutaneous injection
- Mechanism
- Cosmetic / topical
- Pathways
- Collagen Synthesis
How GHK-Cu works
Activates genes involved in tissue repair, collagen synthesis, and anti-inflammatory responses. The copper molecule helps deliver essential minerals directly to skin cells for regeneration.
What research has looked at
- Stimulates collagen and elastin production
- Reduces fine lines and wrinkles
- Improves skin firmness and elasticity
- Promotes wound healing
- May support hair follicle health
Evidence level: Early human data. Only small or early-phase studies in people so far. These are areas studied or reported, not promised effects.
Reported side effects and risks
- Mild skin irritation (topical use)
- Redness at application site
- Rare allergic reactions
- Generally very well-tolerated
- Topical forms considered safe
Sources
- PubMed research on GHK-Cu copper peptide skin regeneration · NIH · National Library of Medicine
- StatPearls / NCBI Bookshelf on GHK copper tripeptide · NCBI Bookshelf
- DrugBank record for copper peptide GHK · DrugBank
Track GHK-Cu in Peptide Vault
Log every dose, set reminders on your own schedule, rotate injection sites and keep your vials organized. Peptide Vault records what you enter. It doesn't recommend compounds or doses. iPhone, on-device.
Related compounds
GHK-Cu FAQ
What is GHK-Cu?
A naturally occurring peptide in human blood that decreases with age. When bound to copper, it becomes a powerful signal for tissue remodeling and skin repair.
How does GHK-Cu work?
Activates genes involved in tissue repair, collagen synthesis, and anti-inflammatory responses. The copper molecule helps deliver essential minerals directly to skin cells for regeneration.
Is GHK-Cu FDA approved?
No. GHK-Cu is used as a cosmetic or over-the-counter ingredient, not as an approved drug. Evidence level: early human data. Only small or early-phase studies in people so far.
What is the half-life of GHK-Cu?
Reported half-life: ~12 hours (topical effects persist longer).
How is GHK-Cu taken?
Topical cream/serum or subcutaneous injection.
What side effects have been reported with GHK-Cu?
Reported in the sources: Mild skin irritation (topical use); Redness at application site; Rare allergic reactions; Generally very well-tolerated; Topical forms considered safe.
Educational summary compiled from the sources listed above. Not medical advice. Peptide Vault does not sell, source or recommend any compound. Talk to a qualified clinician before starting or changing anything.