Approved & therapeutic
DSIP
Delta Sleep Inducing Peptide
A neuropeptide naturally found in the brain that helps regulate sleep cycles. Named for its ability to promote deep, restorative delta-wave sleep.
Also known as: Delta Sleep-Inducing Peptide
- Status
- DSIP is a research compound and not approved by the FDA for human use.
- Evidence
- Preclinical. Evidence comes from animal or lab studies; effects in people are not established.
- Half-life
- ~15-25 minutes (effects last through the night)
- How it's taken
- Subcutaneous injection or intranasal
- Mechanism
- Other
How DSIP works
Modulates sleep architecture by influencing the ratio of different sleep stages. Promotes delta-wave (deep) sleep, which is when your body does most of its physical repair and memory consolidation.
What research has looked at
- Improved deep sleep quality
- Better sleep onset
- Stress and cortisol reduction
- May help normalize disrupted sleep patterns
- Supports natural circadian rhythm
Evidence level: Preclinical. Evidence comes from animal or lab studies; effects in people are not established. These are areas studied or reported, not promised effects.
Reported side effects and risks
- Morning grogginess
- Mild headache
- Low blood pressure in some users
- Limited clinical trial data
- Not FDA-approved
Sources
- PubMed research on delta sleep inducing peptide DSIP · NIH · National Library of Medicine
- DrugBank record for delta sleep inducing peptide · DrugBank
- StatPearls / NCBI Bookshelf on delta sleep inducing peptide · NCBI Bookshelf
Track DSIP in Peptide Vault
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Related compounds
DSIP FAQ
What is DSIP?
A neuropeptide naturally found in the brain that helps regulate sleep cycles. Named for its ability to promote deep, restorative delta-wave sleep.
How does DSIP work?
Modulates sleep architecture by influencing the ratio of different sleep stages. Promotes delta-wave (deep) sleep, which is when your body does most of its physical repair and memory consolidation.
Is DSIP FDA approved?
No. DSIP is a research compound and not approved by the FDA for human use. Evidence level: preclinical. Evidence comes from animal or lab studies; effects in people are not established.
What is the half-life of DSIP?
Reported half-life: ~15-25 minutes (effects last through the night).
How is DSIP taken?
Subcutaneous injection or intranasal.
What side effects have been reported with DSIP?
Reported in the sources: Morning grogginess; Mild headache; Low blood pressure in some users; Limited clinical trial data; Not FDA-approved.
Educational summary compiled from the sources listed above. Not medical advice. Peptide Vault does not sell, source or recommend any compound. Talk to a qualified clinician before starting or changing anything.